Rab11 (RAB11B) (NM_004218) Human Mass Spec Standard

Specifications

Product Data
Description	RAB11B MS Standard C13 and N15-labeled recombinant protein (NP_004209)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC222162
Predicted MW	24.5 kDa
Protein Sequence	Sequence Link (showhide) >RC222162 protein sequence Red=Cloning site Green=Tags(s) MGTRDDEYDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGQ ERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDLRHLRAVPTDEAR AFAEKNNLSFIETSALDSTNVEEAFKNILTEIYRIVSQKQIADRAAHDESPGNNVVDISVPPTTDGQKPN KLQCCQNL TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_004209
RefSeq Size	1635
RefSeq ORF	654
Synonyms	H-YPT3; NDAGSCW
Locus ID	9230
Cytogenetics	19p13.2
Summary	The Ras superfamily of small GTP-binding proteins, which includes the Ras (see MIM 190020), Ral (see MIM 179550), Rho (see MIM 165390), Rap (see MIM 179520), and Rab (see MIM 179508) families, is involved in controlling a diverse set of essential cellular functions. The Rab family, including RAB11B, appears to play a critical role in regulating exocytotic and endocytotic pathways (summary by Zhu et al., 1994 [PubMed 7811277]).[supplied by OMIM, Nov 2010]
Protein Families	Druggable Genome
Protein Pathways	Endocytosis

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