AMD1 (NM_001634) Human Mass Spec Standard

Specifications

Product Data
Description	AMD1 MS Standard C13 and N15-labeled recombinant protein (NP_001625)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC221424
Predicted MW	38.2 kDa
Protein Sequence	Sequence Link (showhide) >RC221424 representing NM_001634 Red=Cloning site Green=Tags(s) MEAAHFFEGTEKLLEVWFSRQQPDANQGSGDLRTIPRSEWDILLKDVQCSIISVTKTDKQEAYVLSESSM FVSKRRFILKTCGTTLLLKALVPLLKLARDYSGFDSIQSFFYSRKNFMKPSHQGYPHRNFQEEIEFLNAI FPNGAAYCMGRMNSDCWYLYTLDFPESRVISQPDQTLEILMSELDPAVMDQFYMKDGVTAKDVTRESGIR DLIPGSVIDATMFNPCGYSMNGMKSDGTYWTIHITPEPEFSYVSFETNLSQTSYDDLIRKVVEVFKPGKF VTTLFVNQSSKCRTVLASPQKIEGFKRLDCQSAMFNDYNFVFTSFAKKQQQQQS TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_001625
RefSeq Size	3421
RefSeq ORF	1002
Synonyms	ADOMETDC; AMD; SAMDC
Locus ID	262
Cytogenetics	6q21
Summary	This gene encodes an important intermediate enzyme in polyamine biosynthesis. The polyamines spermine, spermidine, and putrescine are low-molecular-weight aliphatic amines essential for cellular proliferation and tumor promotion. Multiple alternatively spliced transcript variants have been identified. Pseudogenes of this gene are found on chromosomes 5, 6, 10, X and Y. [provided by RefSeq, Dec 2013]
Protein Families	Druggable Genome
Protein Pathways	Arginine and proline metabolism, Cysteine and methionine metabolism, Metabolic pathways

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