CYP11B1 (NM_001026213) Human Mass Spec Standard

CAT#: PH321240

CYP11B1 MS Standard C13 and N15-labeled recombinant protein (NP_001021384)



  View other "CYP11B1" proteins (5)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Rabbit Polyclonal Anti-CYP11B1 Antibody
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Transient overexpression lysate of cytochrome P450, family 11, subfamily B, polypeptide 1 (CYP11B1), nuclear gene encoding mitochondrial protein, transcript variant 1
    • 100 ug

CNY 4,840.00

Specifications

Product Data
Description CYP11B1 MS Standard C13 and N15-labeled recombinant protein (NP_001021384)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC221240
Predicted MW 49.7 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_001021384
RefSeq Size 3353
RefSeq ORF 1311
Synonyms CPN1; CYP11B; FHI; P450C11
Locus ID 1584
Cytogenetics 8q24.3
Summary This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and is involved in the conversion of progesterone to cortisol in the adrenal cortex. Mutations in this gene cause congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency. Transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, P450
Protein Pathways Androgen and estrogen metabolism, C21-Steroid hormone metabolism, Metabolic pathways
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