ZIC2 (NM_007129) Human Mass Spec Standard

CAT#: PH320798

ZIC2 MS Standard C13 and N15-labeled recombinant protein (NP_009060)



  View other "ZIC2" proteins (3)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (2)
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Specifications

Product Data
Description ZIC2 MS Standard C13 and N15-labeled recombinant protein (NP_009060)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC220798
Predicted MW 54.8 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_009060
RefSeq Size 2698
RefSeq ORF 1596
Synonyms HPE5
Locus ID 7546
Cytogenetics 13q32.3
Summary This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. This protein functions as a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. Expansion of an alanine repeat in the C-terminus of the encoded protein and other mutations in this gene cause holoprosencephaly type 5. Holoprosencephaly is the most common structural anomaly of the human brain. A polyhistidine tract polymorphism in this gene may be associated with increased risk of neural tube defects. This gene is closely linked to a gene encoding zinc finger protein of the cerebellum 5, a related family member on chromosome 13. [provided by RefSeq, Jul 2016]
Protein Families Druggable Genome
Protein Pathways Hedgehog signaling pathway
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