RIPPLY2 (NM_001009994) Human Mass Spec Standard

Specifications

Product Data
Description	RIPPLY2 MS Standard C13 and N15-labeled recombinant protein (NP_001009994)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC220725
Predicted MW	13.9 kDa
Protein Sequence	Sequence Link (showhide) >RC220725 protein sequence Red=Cloning site Green=Tags(s) MENAGGAEGTESGAAACAATDGPTRRAGADSGYAGFWRPWVDAGGKKEEETPNHAAEAMPDGPGMTAASG KLYQFRHPVRLFWPKSKCYDYLYQEAEALLKNFPIQATISFYEDSDSEDEIEDLTCEN TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_001009994
RefSeq Size	674
RefSeq ORF	384
Synonyms	C6orf159; dJ237I15.1; SCDO6
Locus ID	134701
Cytogenetics	6q14.2
Summary	This gene encodes a nuclear protein that belongs to a novel family of proteins required for vertebrate somitogenesis. Members of this family have a tetrapeptide WRPW motif that is required for interaction with the transcriptional repressor Groucho and a carboxy-terminal Ripply homology domain/Bowline-DSCR-Ledgerline conserved region required for transcriptional repression. Null mutant mice die soon after birth and display defects in axial skeleton segmentation due to defective somitogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]

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