PTPD1 (PTPN21) (NM_007039) Human Mass Spec Standard

CAT#: PH320032

PTPN21 MS Standard C13 and N15-labeled recombinant protein (NP_008970)



  View other "PTPD1" proteins (3)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (2)
Transient overexpression lysate of protein tyrosine phosphatase, non-receptor type 21 (PTPN21)
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Rabbit Polyclonal Anti-PTPN21 Antibody
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Specifications

Product Data
Description PTPN21 MS Standard C13 and N15-labeled recombinant protein (NP_008970)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC220032
Predicted MW 133.1 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_008970
RefSeq Size 4234
RefSeq ORF 3522
Synonyms PTPD1; PTPRL10
Locus ID 11099
Cytogenetics 14q31.3
Summary The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal domain, similar to cytoskeletal- associated proteins including band 4.1, ezrin, merlin, and radixin. This PTP was shown to specially interact with BMX/ETK, a member of Tec tyrosine kinase family characterized by a multimodular structures including PH, SH3, and SH2 domains. The interaction of this PTP with BMX kinase was found to increase the activation of STAT3, but not STAT2 kinase. Studies of the similar gene in mice suggested the possible roles of this PTP in liver regeneration and spermatogenesis. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Phosphatase
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