PCDHGA12 (NM_003735) Human Mass Spec Standard

CAT#: PH319857

PCDHGA12 MS Standard C13 and N15-labeled recombinant protein (NP_003726)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (1)
Transient overexpression lysate of protocadherin gamma subfamily A, 12 (PCDHGA12), transcript variant 1
    • 100 ug

CNY 4,840.00

Specifications

Product Data
Description PCDHGA12 MS Standard C13 and N15-labeled recombinant protein (NP_003726)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC219857
Predicted MW 100.96 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_003726
RefSeq Size 4774
RefSeq ORF 2796
Synonyms CDH21; FIB3; PCDH-GAMMA-A12
Locus ID 26025
Cytogenetics 5q31.3
Summary This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. [provided by RefSeq, Jul 2008]
Protein Families Transmembrane
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