Acid sphingomyelinase (SMPD1) (NM_000543) Human Mass Spec Standard
CAT#: PH319758
SMPD1 MS Standard C13 and N15-labeled recombinant protein (NP_000534)
View other "Acid sphingomyelinase" proteins (5)
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CNY 14,250.00
CNY 4,840.00
CNY 1,999.00
CNY 2,700.00
Specifications
Product Data | |
Description | SMPD1 MS Standard C13 and N15-labeled recombinant protein (NP_000534) |
Species | Human |
Expression Host | HEK293 |
Expression cDNA Clone or AA Sequence | RC219758 |
Predicted MW | 69.94 kDa |
Protein Sequence |
>RC219758 representing NM_000543
Red=Cloning site Green=Tags(s) MPRYGASLRQSCPRSGREQGQDGTAGAPGLLWMGLVLALALALALALALSDSRVLWAPAEAHPLSPQGHP ARLHRIVPRLRDVFGWGNLTCPICKGLFTAINLGLKKEPNVARVGSVAIKLCNLLKIAPPAVCQSIVHLF EDDMVEVWRRSVLSPSEACGLLLGSTCGHWDIFSSWNISLPTVPKPPPKPPSPPAPGAPVSRILFLTDLH WDHDYLEGTDPDCADPLCCRRGSGLPPASRPGAGYWGEYSKCDLPLRTLESLLSGLGPAGPFDMVYWTGD IPAHDVWHQTRQDQLRALTTVTALVRKFLGPVPVYPAVGNHESTPVNSFPPPFIEGNHSSRWLYEAMAKA WEPWLPAEALRTLRIGGFYALSPYPGLRLISLNMNFCSRENFWLLINSTDPAGQLQWLVGELQAAEDRGD KVHIIGHIPPGHCLKSWSWNYYRIVARYENTLAAQFFGHTHVDEFEVFYDEETLSRPLAVAFLAPSATTY IGLNPGYRVYQIDGNYSGSSHVVLDHETYILNLTQANIPGAIPHWQLLYRARETYGLPNTLPTAWHNLVY RMRGDMQLFQTFWFLYHKGHPPSEPCGTPCRLATLCAQLSARADSPALCRHLMPDGSLPEAQSLWPRPLF C TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Tag | C-Myc/DDK |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration | >0.05 µg/µL as determined by microplate BCA method |
Labeling Method | Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine |
Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
Reference Data | |
RefSeq | NP_000534 |
RefSeq Size | 2473 |
RefSeq ORF | 1893 |
Synonyms | ASM; ASMASE; NPD |
Locus ID | 6609 |
Cytogenetics | 11p15.4 |
Summary | The protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB). Multiple transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2010] |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Lysosome, Metabolic pathways, Sphingolipid metabolism |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC400191 | SMPD1 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 1,470.00 |
|
LC423515 | SMPD1 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 1,470.00 |
|
LY400191 | Transient overexpression lysate of sphingomyelin phosphodiesterase 1, acid lysosomal (SMPD1), transcript variant ASM-1 |
CNY 4,840.00 |
|
LY423515 | Transient overexpression lysate of sphingomyelin phosphodiesterase 1, acid lysosomal (SMPD1), transcript variant ASM-2 |
CNY 4,840.00 |
|
TP319758 | Purified recombinant protein of Homo sapiens sphingomyelin phosphodiesterase 1, acid lysosomal (SMPD1), transcript variant 1, 20 µg |
CNY 2,900.00 |
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