IL36 alpha (IL36A) (NM_014440) Human Mass Spec Standard

Specifications

Product Data
Description	IL1F6 MS Standard C13 and N15-labeled recombinant protein (NP_055255)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC219328
Predicted MW	17.7 kDa
Protein Sequence	Sequence Link (showhide) >Peptide sequence encoded by RC219328 Blue=ORF Red=Cloning site Green=Tag(s) MEKALKIDTPQRGSIQDINHRVWVLQDQTLIAVPRKDRMSPVTIALISCRHVETLEKDRGNPIYLGLNG LNLCLMCAKVGDQPTLQLKEKDIMDLYNQPEPVKSFLFYHSQSGRNSTFESVAFPGWFIAVSSEGGCPL ILTQELGKANTTDFGLTMLF TRTRPLEQKLISEEDLAANDILDYKDDDDKV Recombinant protein using RC219328 also available, TP319328M
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_055255
RefSeq Size	477
RefSeq ORF	474
Synonyms	FIL1; FIL1(EPSILON); FIL1E; IL-1F6; IL1(EPSILON); IL1F6
Locus ID	27179
Cytogenetics	2q14.1
Summary	The protein encoded by this gene is a cytokine that can activate NF-kappa-B and MAPK signaling pathways to generate an inflammatory response. The encoded protein functions primarily in skin and demonstrates increased expression in psoriasis. In addition, decreased expression of this gene has been linked to a poor prognosis in both hepatocellular carcinoma and colorectal cancer patients. [provided by RefSeq, Nov 2015]
Protein Families	Druggable Genome, Secreted Protein

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