HFE (NM_139006) Human Mass Spec Standard

CAT#: PH319316

HFE MS Standard C13 and N15-labeled recombinant protein (NP_620575)



  View other "HFE" proteins (11)

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CNY 14,250.00


货期*
5周

规格
    • 10 ug

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Specifications

Product Data
Description HFE MS Standard C13 and N15-labeled recombinant protein (NP_620575)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC219316
Predicted MW 36.2 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_620575
RefSeq Size 1045
RefSeq ORF 1002
Synonyms HFE1; HH; HLA-H; MVCD7; TFQTL2
Locus ID 3077
Cytogenetics 6p22.2
Summary The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Transmembrane
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