MAGEA5P (NM_021049) Human Mass Spec Standard

Specifications

Product Data
Description	MAGEA5 MS Standard C13 and N15-labeled recombinant protein (NP_066387)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC218575
Predicted MW	13 kDa
Protein Sequence	Sequence Link (showhide) >RC218575 protein sequence Red=Cloning site Green=Tags(s) MSLEQKSQHCKPEEGLDTQEEALGLVGVQAATTEEQEAVSSSSPLVPGTLGEVPAAGSPGPLKSPQGASA IPTAIDFTLWRQSIKGSSNQEEEGPSTSPDPESVFRAALSKKVADLIHFLLLKY TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_066387
RefSeq Size	1664
RefSeq ORF	372
Synonyms	CT1.5; MAGE5; MAGEA4
Locus ID	4104
Cytogenetics	Xq28
Summary	This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. This MAGEA gene is interpreted to be a pseudogene. Read-through transcription exists between this gene and the upstream melanoma antigen family A, 10 (MAGEA10) gene. [provided by RefSeq, Dec 2020]

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