TEM8 (ANTXR1) (NM_053034) Human Mass Spec Standard

CAT#: PH318473

ANTXR1 MS Standard C13 and N15-labeled recombinant protein (NP_444262)



  View other "TEM8" proteins (7)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description ANTXR1 MS Standard C13 and N15-labeled recombinant protein (NP_444262)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC218473
Predicted MW 38.3 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_444262
RefSeq Size 1454
RefSeq ORF 1104
Synonyms ATR; GAPO; TEM8
Locus ID 84168
Cytogenetics 2p13.3
Summary This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described. [provided by RefSeq, Oct 2008]
Protein Families Druggable Genome, Transmembrane
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