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TRIM72 (NM_001008274) Human Mass Spec Standard
CAT＃: PH318023
TRIM72 MS Standard C13 and N15-labeled recombinant protein (NP_001008275)
View other "TRIM72" proteins (9)
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CNY 14,250.00
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Specifications
| Product Data | |
| Description | TRIM72 MS Standard C13 and N15-labeled recombinant protein (NP_001008275) |
| Species | Human |
| Expression Host | HEK293 |
| Expression cDNA Clone or AA Sequence | RC218023 |
| Predicted MW | 52.6 kDa |
| Protein Sequence |
>RC218023 representing NM_001008274
Red=Cloning site Green=Tags(s) MSAAPGLLHQELSCPLCLQLFDAPVTAECGHSFCRACLGRVAGEPAADGTVLCPCCQAPTRPQALSTNLQ LARLVEGLAQVPQGHCEEHLDPLSIYCEQDRALVCGVCASLGSHRGHRLLPAAEAHARLKTQLPQQKLQL QEACMRKEKSVAVLEHQLVEVEETVRQFRGAVGEQLGKMRVFLAALEGSLDREAERVRGEAGVALRRELG SLNSYLEQLRQMEKVLEEVADKPQTEFLMKYCLVTSRLQKILAESPPPARLDIQLPIISDDFKFQVWRKM FRALMPALEELTFDPSSAHPSLVVSSSGRRVECSEQKAPPAGEDPRQFDKAVAVVAHQQLSEGEHYWEVD VGDKPRWALGVIAAEAPRRGRLHAVPSQGLWLLGLREGKILEAHVEAKEPRALRSPERRPTRIGLYLSFG DGVLSFYDASDADALVPLFAFHERLPRPVYPFFDVCWHDKGKNAQPLLLVGPEGAEA TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Tag | C-Myc/DDK |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Labeling Method | Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
| Reference Data | |
| RefSeq | NP_001008275 |
| RefSeq Size | 2098 |
| RefSeq ORF | 1431 |
| Synonyms | MG53 |
| Locus ID | 493829 |
| Cytogenetics | 16p11.2 |
| Summary | Muscle-specific protein that plays a central role in cell membrane repair by nucleating the assembly of the repair machinery at injury sites. Specifically binds phosphatidylserine. Acts as a sensor of oxidation: upon membrane damage, entry of extracellular oxidative environment results in disulfide bond formation and homooligomerization at the injury site. This oligomerization acts as a nucleation site for recruitment of TRIM72-containing vesicles to the injury site, leading to membrane patch formation. Probably acts upstream of the Ca(2+)-dependent membrane resealing process. Required for transport of DYSF to sites of cell injury during repair patch formation. Regulates membrane budding and exocytosis. May be involved in the regulation of the mobility of KCNB1-containing endocytic vesicles (By similarity).[UniProtKB/Swiss-Prot Function] |
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Other Versions
| SKU | Description | Size | Price |
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| LC423413 | TRIM72 HEK293T cell transient overexpression lysate (as WB positive control) |
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| TP318023 | Recombinant protein of human tripartite motif-containing 72 (TRIM72), 20 µg |
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| TP750051 | Purified recombinant protein of Human MG53,full length, expressed in E. coli,50ug |
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| TP750052 | Purified recombinant protein of Human MG53, mutant Cys14Ala, expressed in E. coli,50ug |
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| TP750131 | Purified recombinant protein of Human MG53,Ala123-Ala477, expressed in E. coli,50ug |
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| TP750134 | Purified recombinant protein of Human MG53,Met1-Asp270, expressed in E. coli,50ug |
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| TP750135 | Purified recombinant protein of Human MG53,Asp271-Ala477, expressed in E. coli,50ug |
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| TP750136 | Purified recombinant protein of Human MG53, Ala58-End, tag free, expressed in E.coli, 50ug |
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