HNF 4 alpha (HNF4A) (NM_178850) Human Mass Spec Standard

CAT#: PH317924

HNF4A MS Standard C13 and N15-labeled recombinant protein (NP_849181)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description HNF4A MS Standard C13 and N15-labeled recombinant protein (NP_849181)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC217924
Predicted MW 46.4 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_849181
RefSeq Size 1600
RefSeq ORF 1251
Synonyms FRTS4; HNF4; HNF4a7; HNF4a8; HNF4a9; HNF4alpha; MODY; MODY1; NR2A1; NR2A21; TCF; TCF-14; TCF14
Locus ID 3172
Cytogenetics 20q13.12
Summary The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms. [provided by RefSeq, Apr 2012]
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Nuclear Hormone Receptor, Transcription Factors
Protein Pathways Maturity onset diabetes of the young
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