Germinal Center Kinase (MAP4K2) (NM_004579) Human Mass Spec Standard
CAT#: PH317608
MAP4K2 MS Standard C13 and N15-labeled recombinant protein (NP_004570)
View other "Germinal Center Kinase" proteins (3)
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CNY 19,520.00
Specifications
Product Data | |
Description | MAP4K2 MS Standard C13 and N15-labeled recombinant protein (NP_004570) |
Species | Human |
Expression Host | HEK293 |
Expression cDNA Clone or AA Sequence | RC217608 |
Predicted MW | 91.4 kDa |
Protein Sequence |
>RC217608 representing NM_004579
Red=Cloning site Green=Tags(s) MALLRDVSLQDPRDRFELLQRVGAGTYGDVYKARDTVTSELAAVKIVKLDPGDDISSLQQEITILRECRH PNVVAYIGSYLRNDRLWICMEFCGGGSLQEIYHATGPLEERQIAYVCREALKGLHHLHSQGKIHRDIKGA NLLLTLQGDVKLADFGVSGELTASVAKRRSFIGTPYWMAPEVAAVERKGGYNELCDVWALGITAIELGEL QPPLFHLHPMRALMLMSKSSFQPPKLRDKTRWTQNFHHFLKLALTKNPKKRPTAEKLLQHPFTTQQLPRA LLTQLLDKASDPHLGTPSPEDCELETYDMFPDTIHSRGQHGPAERTPSEIQFHQVKFGAPRRKETDPLNE PWEEEWTLLGKEELSGSLLQSVQEALEERSLTIRSASEFQELDSPDDTMGTIKRAPFLGPLPTDPPAEEP LSSPPGTLPPPPSGPNSSPLLPTAWATMKQREDPERSSCHGLPPTPKVHMGACFSKVFNGCPLRIHAAVT WIHPVTRDQFLVVGAEEGIYTLNLHELHEDTLEKLISHRCSWLYCVNNVLLSLSGKSTHIWAHDLPGLFE QRRLQQQVPLSIPTNRLTQRIIPRRFALSTKIPDTKGCLQCRVVRNPYTGATFLLAALPTSLLLLQWYEP LQKFLLLKNFSSPLPSPAGMLEPLVLDGKELPQVCVGAEGPEGPGCRVLFHVLPLEAGLTPDILIPPEGI PGSAQQVIQVDRDTILVSFERCVRIVNMQGEPTATLAPELTFDFPIETVVCLQDSVLAFWSHGMQGRSLD TNEVTQEITDETRIFRVLGAHRDIILESIPTDNPEAHSNLYILTGHQSTY TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Tag | C-Myc/DDK |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration | >0.05 µg/µL as determined by microplate BCA method |
Labeling Method | Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine |
Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
Reference Data | |
RefSeq | NP_004570 |
RefSeq Size | 2964 |
RefSeq ORF | 2460 |
Synonyms | BL44; GCK; RAB8IP |
Locus ID | 5871 |
Cytogenetics | 11q13.1 |
Summary | The protein encoded by this gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015] |
Protein Families | Druggable Genome, Protein Kinase |
Protein Pathways | MAPK signaling pathway |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC417889 | MAP4K2 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 1,470.00 |
|
LY417889 | Transient overexpression lysate of mitogen-activated protein kinase kinase kinase kinase 2 (MAP4K2) |
CNY 4,840.00 |
|
TP317608 | Recombinant protein of human mitogen-activated protein kinase kinase kinase kinase 2 (MAP4K2), 20 µg |
CNY 2,900.00 |
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