RHOC (NM_175744) Human Mass Spec Standard

CAT#: PH317556

RHOC MS Standard C13 and N15-labeled recombinant protein (NP_786886)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description RHOC MS Standard C13 and N15-labeled recombinant protein (NP_786886)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC217556
Predicted MW 21.8 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_786886
RefSeq Size 1116
RefSeq ORF 579
Synonyms ARH9; ARHC; H9; RHOH9
Locus ID 389
Cytogenetics 1p13.2
Summary This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome
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