Glycophorin C (GYPC) (NM_016815) Human Mass Spec Standard

Specifications

Product Data
Description	GYPC MS Standard C13 and N15-labeled recombinant protein (NP_058131)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC217103
Predicted MW	11.7 kDa
Protein Sequence	Sequence Link (showhide) >RC217103 representing NM_016815 Red=Cloning site Green=Tags(s) MWSTRSPNSTAWPLSLEPDPGMSGWPDGRMETSTPTIMDIVVIAGVIAAVAIVLVSLLFVMLRYMYRHKG TYHTNEAKGTEFAESADAALQGDPALQDAGDSSRKEYFI TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_058131
RefSeq Size	1019
RefSeq ORF	327
Synonyms	CD236; CD236R; GE; GE:GPC:GPD:GYPD; GPC; GPD; GYPD; PAS-2; PAS-2'
Locus ID	2995
Cytogenetics	2q14.3
Summary	Glycophorin C (GYPC) is an integral membrane glycoprotein. It is a minor species carried by human erythrocytes, but plays an important role in regulating the mechanical stability of red cells. A number of glycophorin C mutations have been described. The Gerbich and Yus phenotypes are due to deletion of exon 3 and 2, respectively. The Webb and Duch antigens, also known as glycophorin D, result from single point mutations of the glycophorin C gene. The glycophorin C protein has very little homology with glycophorins A and B. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]
Protein Families	Druggable Genome, Transmembrane

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.