USP8 (NM_005154) Human Mass Spec Standard

CAT#: PH316926

USP8 MS Standard C13 and N15-labeled recombinant protein (NP_005145)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description USP8 MS Standard C13 and N15-labeled recombinant protein (NP_005145)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC216926
Predicted MW 127.3 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_005145
RefSeq Size 4250
RefSeq ORF 3354
Synonyms HumORF8; PITA4; SPG59; UBPY
Locus ID 9101
Cytogenetics 15q21.2
Summary This gene encodes a protein that belongs to the ubiquitin-specific processing protease family of proteins. The encoded protein is thought to regulate the morphology of the endosome by ubiquitination of proteins on this organelle and is involved in cargo sorting and membrane trafficking at the early endosome stage. This protein is required for the cell to enter the S phase of the cell cycle and also functions as a positive regulator in the Hedgehog signaling pathway in development. Pseudogenes of this gene are present on chromosomes 2 and 6. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Protein Families Druggable Genome, Protease
Protein Pathways Endocytosis
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