Aspartate beta hydroxylase (ASPH) (NM_004318) Human Mass Spec Standard

CAT#: PH316796

ASPH MS Standard C13 and N15-labeled recombinant protein (NP_004309)



  View other "Aspartate beta hydroxylase" proteins (15)

Need it in bulk or customized?
Get a free quote

CNY 19,520.00


货期*
4周

规格
    • 10 ug

Product images

经常一起买 (2)
Rabbit Polyclonal Anti-ASPH
    • 100 ul

CNY 5,250.00


Transient overexpression lysate of aspartate beta-hydroxylase (ASPH), transcript variant 3
    • 100 ug

CNY 3,080.00

Specifications

Product Data
Description ASPH MS Standard C13 and N15-labeled recombinant protein (NP_004309)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC216796
Predicted MW 85.7 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_004309
RefSeq Size 2452
RefSeq ORF 2274
Synonyms AAH; BAH; CASQ2BP1; FDLAB; HAAH; JCTN; junctin
Locus ID 444
Cytogenetics 8q12.3
Summary This gene is thought to play an important role in calcium homeostasis. The gene is expressed from two promoters and undergoes extensive alternative splicing. The encoded set of proteins share varying amounts of overlap near their N-termini but have substantial variations in their C-terminal domains resulting in distinct functional properties. The longest isoforms (a and f) include a C-terminal Aspartyl/Asparaginyl beta-hydroxylase domain that hydroxylates aspartic acid or asparagine residues in the epidermal growth factor (EGF)-like domains of some proteins, including protein C, coagulation factors VII, IX, and X, and the complement factors C1R and C1S. Other isoforms differ primarily in the C-terminal sequence and lack the hydroxylase domain, and some have been localized to the endoplasmic and sarcoplasmic reticulum. Some of these isoforms are found in complexes with calsequestrin, triadin, and the ryanodine receptor, and have been shown to regulate calcium release from the sarcoplasmic reticulum. Some isoforms have been implicated in metastasis. [provided by RefSeq, Sep 2009]
Protein Families Druggable Genome, Transmembrane
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Documents

Other Versions

You may also need

其它Aspartate beta hydroxylase产品

Customer Reviews 
Loading...