PYCR1 (NM_153824) Human Mass Spec Standard

Specifications

Product Data
Description	PYCR1 MS Standard C13 and N15-labeled recombinant protein (NP_722546)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC216359
Predicted MW	33.2 kDa
Protein Sequence	Sequence Link (showhide) >RC216359 representing NM_153824 Red=Cloning site Green=Tags(s) MSVGFIGAGQLAFALAKGFTAAGVLAAHKIMASSPDMDLATVSALRKMGVKLTPHNKETVQHSDVLFLAV KPHIIPFILDEIGADIEDRHIVVSCAAGVTISSIEKKLSAFRPAPRVIRCMTNTPVVVREGATVYATGTH AQVEDGRLMEQLLSSVGFCTEVEEDLIDAVTGLSGSGPAYAFTALDALADGGVKMGLPRRLAVRLGAQAL LGAAKMLLHSEQHPGQLKDNVSSPGGATIHALHVLESGGFRSLLINAVEASCIRTRELQSMADQEQVSPA AIKKTILDKDHLPLELGSPEGLHPLLLQYQLARAPS TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_722546
RefSeq Size	1768
RefSeq ORF	948
Synonyms	ARCL2B; ARCL3B; P5C; P5CR; PIG45; PP222; PRO3; PYCR
Locus ID	5831
Cytogenetics	17q25.3
Summary	This gene encodes an enzyme that catalyzes the NAD(P)H-dependent conversion of pyrroline-5-carboxylate to proline. This enzyme may also play a physiologic role in the generation of NADP(+) in some cell types. The protein forms a homopolymer and localizes to the mitochondrion. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Protein Pathways	Arginine and proline metabolism, Metabolic pathways

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