C1orf86 (FAAP20) (NM_182533) Human Mass Spec Standard

Specifications

Product Data
Description	C1orf86 MS Standard C13 and N15-labeled recombinant protein (NP_872339)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC215561
Predicted MW	19.6 kDa
Protein Sequence	Sequence Link (showhide) >RC215561 representing NM_182533 Red=Cloning site Green=Tags(s) MEAARRPRLGLSRRRPPPAGGPSGGRPWFLLGGDERERLWAELLRTVSPELILDHEVPSLPAFPGQEPRC GPEPTEVFTVGPKTFSWTPFPPDLWGPGRSYRLLHGAGGHLESPARSLPQRPAPDPCRAPRVEQQPSVEG AAALRSCPMCQKEFAPRLTQLDVDSHLAQCLAESTEDVTW TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_872339
RefSeq Size	745
RefSeq ORF	540
Synonyms	C1orf86; FP7162
Locus ID	199990
Cytogenetics	1p36.33
Summary	Component of the Fanconi anemia (FA) complex required to recruit the FA complex to DNA interstrand cross-links (ICLs) and promote ICLs repair. Following DNA damage recognizes and binds 'Lys-63'-linked ubiquitin generated by RNF8 at ICLs and recruits other components of the FA complex. Promotes translesion synthesis via interaction with REV1.[UniProtKB/Swiss-Prot Function]

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