PAX3 (NM_181457) Human Mass Spec Standard

CAT#: PH315181

PAX3 MS Standard C13 and N15-labeled recombinant protein (NP_852122)



  View other "PAX3" proteins (10)

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CNY 14,250.00


货期*
5周

规格
    • 10 ug

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Specifications

Product Data
Description PAX3 MS Standard C13 and N15-labeled recombinant protein (NP_852122)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC215181
Predicted MW 52.8 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_852122
RefSeq Size 3193
RefSeq ORF 1437
Synonyms CDHS; HUP2; WS1; WS3
Locus ID 5077
Cytogenetics 2q36.1
Summary This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2;13)(q35;q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini. [provided by RefSeq, Jul 2008]
Protein Families Adult stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Transcription Factors
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