PDGF AA (PDGFA) (NM_033023) Human Mass Spec Standard

CAT#: PH314164

PDGFA MS Standard C13 and N15-labeled recombinant protein (NP_148983)



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CNY 14,250.00


货期*
5周

规格
    • 10 ug

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Specifications

Product Data
Description PDGFA MS Standard C13 and N15-labeled recombinant protein (NP_148983)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC214164
Predicted MW 20.1 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_148983
RefSeq Size 2749
RefSeq ORF 588
Synonyms PDGF-A; PDGF1
Locus ID 5154
Cytogenetics 7p22.3
Summary This gene encodes a member of the protein family comprised of both platelet-derived growth factors (PDGF) and vascular endothelial growth factors (VEGF). The encoded preproprotein is proteolytically processed to generate platelet-derived growth factor subunit A, which can homodimerize, or alternatively, heterodimerize with the related platelet-derived growth factor subunit B. These proteins bind and activate PDGF receptor tyrosine kinases, which play a role in a wide range of developmental processes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
Protein Families Druggable Genome
Protein Pathways Cytokine-cytokine receptor interaction, Focal adhesion, Gap junction, Glioma, MAPK signaling pathway, Melanoma, Pathways in cancer, Prostate cancer, Regulation of actin cytoskeleton
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