ATP2B4 (NM_001684) Human Mass Spec Standard

CAT#: PH313835

ATP2B4 MS Standard C13 and N15-labeled recombinant protein (NP_001675)



  View other "ATP2B4" proteins (3)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (2)
Transient overexpression lysate of ATPase, Ca++ transporting, plasma membrane 4 (ATP2B4), transcript variant 2
    • 100 ug

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Rabbit Polyclonal Anti-ATP2B4 Antibody
    • 100 ul

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Specifications

Product Data
Description ATP2B4 MS Standard C13 and N15-labeled recombinant protein (NP_001675)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC213835
Predicted MW 133.8 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_001675
RefSeq Size 8733
RefSeq ORF 3615
Synonyms ATP2B2; MXRA1; PMCA4; PMCA4b; PMCA4x
Locus ID 493
Cytogenetics 1q32.1
Summary The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 4. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Transmembrane
Protein Pathways Calcium signaling pathway
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