ASD3 (MYH6) (NM_002471) Human Mass Spec Standard

Specifications

Product Data
Description	MYH6 MS Standard C13 and N15-labeled recombinant protein (NP_002462)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC213673
Predicted MW	224.2 kDa
Protein Sequence	Sequence Link (showhide) RC213673
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_002462
RefSeq Size	5941
RefSeq ORF	5817
Synonyms	alpha-MHC; ASD3; CMD1EE; CMH14; MYHC; MYHCA; SSS3
Locus ID	4624
Cytogenetics	14q11.2
Summary	Cardiac muscle myosin is a hexamer consisting of two heavy chain subunits, two light chain subunits, and two regulatory subunits. This gene encodes the alpha heavy chain subunit of cardiac myosin. The gene is located approximately 4kb downstream of the gene encoding the beta heavy chain subunit of cardiac myosin. Mutations in this gene cause familial hypertrophic cardiomyopathy and atrial septal defect 3. [provided by RefSeq, Feb 2017]
Protein Pathways	Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM), Tight junction, Viral myocarditis

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