KCNE2 (NM_172201) Human Mass Spec Standard

Specifications

Product Data
Description	KCNE2 MS Standard C13 and N15-labeled recombinant protein (NP_751951)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC211320
Predicted MW	14.5 kDa
Protein Sequence	Sequence Link (showhide) >RC211320 protein sequence Red=Cloning site Green=Tags(s) MSTLSNFTQTLEDVFRRIFITYMDNWRQNTTAEQEALQAKVDAENFYYVILYLMVMIGMFSFIIVAILVS TVKSKRREHSNDPYHQYIVEDWQEKYKSQILNLEESKATIHENIGAAGFKMSP TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_751951
RefSeq Size	809
RefSeq ORF	369
Synonyms	ATFB4; LQT5; LQT6; MIRP1
Locus ID	9992
Cytogenetics	21q22.11
Summary	Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, isk-related subfamily. This member is a small integral membrane subunit that assembles with the KCNH2 gene product, a pore-forming protein, to alter its function. This gene is expressed in heart and muscle and the gene mutations are associated with cardiac arrhythmia. [provided by RefSeq, Jul 2008]
Protein Families	Druggable Genome, Transmembrane

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