Apolipoprotein L 1 (APOL1) (NM_003661) Human Mass Spec Standard

Specifications

Product Data
Description	APOL1 MS Standard C13 and N15-labeled recombinant protein (NP_003652)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC211114
Predicted MW	43.97 kDa
Protein Sequence	Sequence Link (showhide) >RC211114 representing NM_003661 Red=Cloning site Green=Tags(s) MEGAALLRVSVLCIWMSALFLGVGVRAEEAGARVQQNVPSGTDTGDPQSKPLGDWAAGTMDPESSIFIED AIKYFKEKVSTQNLLLLLTDNEAWNGFVAAAELPRNEADELRKALDNLARQMIMKDKNWHDKGQQYRNWF LKEFPRLKSKLEDNIRRLRALADGVQKVHKGTTIANVVSGSLSISSGILTLVGMGLAPFTEGGSLVLLEP GMELGITAALTGITSSTMDYGKKWWTQAQAHDLVIKSLDKLKEVREFLGENISNFLSLAGNTYQLTRGIG KDIRALRRARANLQSVPHASASRPRVTEPISAESGEQVERVNEPSILEMSRGVKLTDVAPVSFFLVLDVV YLVYESKHLHEGAKSETAEELKKVAQELEEKLNILNNNYKILQADQEL TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_003652
RefSeq Size	2856
RefSeq ORF	1194
Synonyms	APO-L; APOL; APOL-I; FSGS4
Locus ID	8542
Cytogenetics	22q12.3
Summary	This gene encodes a secreted high density lipoprotein which binds to apolipoprotein A-I. Apolipoprotein A-I is a relatively abundant plasma protein and is the major apoprotein of HDL. It is involved in the formation of most cholesteryl esters in plasma and also promotes efflux of cholesterol from cells. This apolipoprotein L family member may play a role in lipid exchange and transport throughout the body, as well as in reverse cholesterol transport from peripheral cells to the liver. Several different transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008]
Protein Families	Secreted Protein, Transmembrane

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