PDE4 (PDE4B) (NM_001037341) Human Mass Spec Standard

CAT#: PH310912

PDE4B MS Standard C13 and N15-labeled recombinant protein (NP_001032418)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description PDE4B MS Standard C13 and N15-labeled recombinant protein (NP_001032418)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC210912
Predicted MW 83.3 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_001032418
RefSeq Size 4309
RefSeq ORF 2208
Synonyms DPDE4; PDEIVB
Locus ID 5142
Cytogenetics 1p31.3
Summary This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]
Protein Families Druggable Genome
Protein Pathways Progesterone-mediated oocyte maturation, Purine metabolism
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