PPPDE2 (DESI1) (NM_015704) Human Mass Spec Standard

Specifications

Product Data
Description	PPPDE2 MS Standard C13 and N15-labeled recombinant protein (NP_056519)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC210892
Predicted MW	18.3 kDa
Protein Sequence	Sequence Link (showhide) >RC210892 protein sequence Red=Cloning site Green=Tags(s) MEPPNLYPVKLYVYDLSKGLARRLSPIMLGKQLEGIWHTSIVVHKDEFFFGSGGISSCPPGGTLLGPPDS VVDVGSTEVTEEIFLEYLSSLGESLFRGEAYNLFEHNCNTFSNEVAQFLTGRKIPSYITDLPSEVLSTPF GQALRPLLDSIQIQPPGGSSVGRPNGQS TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_056519
RefSeq Size	3804
RefSeq ORF	504
Synonyms	D15Wsu75e; DeSI-1; DESI2; DJ347H13.4; FAM152B; POST; PPPDE2
Locus ID	27351
Cytogenetics	22q13.2
Summary	Protease which deconjugates SUMO1, SUMO2 and SUMO3 from some substrate proteins. Has isopeptidase but not SUMO-processing activity (By similarity). Desumoylates ZBTB46 (By similarity). Collaborates with UBQLN4 in the export of ubiquitinated proteins from the nucleus to the cytoplasm (PubMed:29666234).[UniProtKB/Swiss-Prot Function]

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