PRKRIR (THAP12) (NM_004705) Human Mass Spec Standard

Specifications

Product Data
Description	PRKRIR MS Standard C13 and N15-labeled recombinant protein (NP_004696)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC210314
Predicted MW	87.7 kDa
Protein Sequence	Sequence Link (showhide) >RC210314 protein sequence Red=Cloning site Green=Tags(s) MPNFCAAPNCTRKSTQSDLAFFRFPRDPARCQKWVENCRRADLEDKTPDQLNKHYRLCAKHFETSMICRT SPYRTVLRDNAIPTIFDLTSHLNNPHSRHRKRIKELSEDKIRTLKQKKIDETSEQEQKHKETNNSNAQNP SEEEGEGQDEDILPLTLEEKENKEYLKSLFEILILMGKQNIPLDGHEADEIPEGLFTPDNFQALLECRIN SGEEVLRKRFETTAVNTLFCSKTQQRQMLEICESCIREETLREVRDSHFFSIITDDVVDIAGEEHLPVLV RFVDESHNLREEFIGFLPYEADAEILAVKFHTMITEKWGLNMEYCRGQAYIVSSGFSSRMKVVASRLLEK YPQAIYTLCSSCALNMWLAKSVPVMGVSVALGTIEEVCSFFHRSPQLLLELDNVISVLFQNSKERGKELK EICHSQWTGRHDAFEILVELLQALVLCLDGINSDTNIRWNNYIAGRAFVLCSAVSDFDFIVTVVVLKNVL SFTRAFGKNLQGQTSDVFFAAGSLTAVLHSLNEVMENIEVYHEFWFEEATNLATKLDIQMKLPGKFRRAH QGNLESQLTSESYYKETLSVPTVEHIIQELKDIFSEQHLKALKCLSLVPSVMGQLKFNTSEEHHADMYRS DLPNPDTLSAELHCWRIKWKHRGKDIELPSTIYEALHLPDIKFFPNVYALLKVLCILPVMKVENERYENG RKRLKAYLRNTLTDQRSSNLALLNINFDIKHDLDLMVDTYIKLYTSKSELPTDNSETVENT TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_004696
RefSeq Size	3202
RefSeq ORF	2283
Synonyms	DAP4; P52rIPK; PRKRIR; THAP0
Locus ID	5612
Cytogenetics	11q13.5
Summary	Upstream regulator of interferon-induced serine/threonine protein kinase R (PKR). May block the PKR-inhibitory function of DNAJC3, resulting in restoration of kinase activity and suppression of cell growth.[UniProtKB/Swiss-Prot Function]
Protein Families	Druggable Genome

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