RPA4 (NM_013347) Human Mass Spec Standard

Specifications

Product Data
Description	RPA4 MS Standard C13 and N15-labeled recombinant protein (NP_037479)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC210239
Predicted MW	28.9 kDa
Protein Sequence	Sequence Link (showhide) >RC210239 protein sequence Red=Cloning site Green=Tags(s) MSKSGFGSYGSISAADGASGGSDQLCERDATPAIKTQRPKVRIQDVVPCNVNQLLSSTVFDPVFKVRGII VSQVSIVGVIRGAEKASNHICYKIDDMTAKPIEARQWFGREKVKQVTPLSVGVYVKVFGILKCPTGTKSL EVLKIHVLEDMNEFTVHILETVNAHMMLDKARRDTTVESVPVSPSEVNDAGDNDESHRNFIQDEVLRLIH ECPHQEGKSIHELRAQLCDLSVKAIKEAIDYLTVEGHIYPTVDREHFKSAD TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_037479
RefSeq Size	1560
RefSeq ORF	783
Synonyms	HSU24186
Locus ID	29935
Cytogenetics	Xq21.33
Summary	This gene encodes a single-stranded DNA-binding protein that is the 30-kDa subunit of the replication protein A complex. Replication protein A is an essential factor for DNA double-strand break repair and cell cycle checkpoint activation. The encoded protein localizes to DNA repair foci and may be involved in the cellular DNA damage response. This protein may also play a role in inhibiting viral replication.[provided by RefSeq, Apr 2010]
Protein Families	Druggable Genome
Protein Pathways	DNA replication, Homologous recombination, Mismatch repair, Nucleotide excision repair

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