PAEP (NM_002571) Human Mass Spec Standard

Specifications

Product Data
Description	PAEP MS Standard C13 and N15-labeled recombinant protein (NP_002562)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC210121
Predicted MW	20.6 kDa
Protein Sequence	Sequence Link (showhide) >RC210121 protein sequence Red=Cloning site Green=Tags(s) MLCLLLTLGVALVCGVPAMDIPQTKQDLELPKLAGTWHSMAMATNNISLMATLKAPLRVHITSLLPTPED NLEIVLHRWENNSCVEKKVLGEKTENPKKFKINYTVANEATLLDTDYDNFLFLCLQDTTTPIQSMMCQYL ARVLVEDDEIMQGFIRAFRPLPRHLWYLLDLKQMEEPCRF TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_002562
RefSeq Size	828
RefSeq ORF	540
Synonyms	GD; GdA; GdF; GdS; PAEG; PEP; PP14; ZIF-1
Locus ID	5047
Cytogenetics	9q34.3
Summary	This gene is a member of the kernel lipocalin superfamily whose members share relatively low sequence similarity but have highly conserved exon/intron structure and three-dimensional protein folding. Most lipocalins are clustered on the long arm of chromosome 9. The encoded glycoprotein has been previously referred to as pregnancy-associated endometrial alpha-2-globulin, placental protein 14, and glycodelin, but has been officially named progestagen-associated endometrial protein. Three distinct forms, with identical protein backbones but different glycosylation profiles, are found in amniotic fluid, follicular fluid and seminal plasma of the reproductive system. These glycoproteins have distinct and essential roles in regulating a uterine environment suitable for pregnancy and in the timing and occurrence of the appropriate sequence of events in the fertilization process. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
Protein Families	Druggable Genome

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