CCL3 (NM_002983) Human Mass Spec Standard

Specifications

Product Data
Description	CCL3 MS Standard C13 and N15-labeled recombinant protein (NP_002974)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC210026
Predicted MW	10.1 kDa
Protein Sequence	Sequence Link (showhide) >RC210026 protein sequence Red=Cloning site Green=Tags(s) MQVSTAALAVLLCTMALCNQFSASLAADTPTACCFSYTSRQIPQNFIADYFETSSQCSKPGVIFLTKRSR QVCADPSEEWVQKYVSDLELSA TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_002974
RefSeq Size	813
RefSeq ORF	276
Synonyms	G0S19-1; LD78ALPHA; MIP-1-alpha; MIP1A; SCYA3
Locus ID	6348
Cytogenetics	17q12
Summary	This locus represents a small inducible cytokine. The encoded protein, also known as macrophage inflammatory protein 1 alpha, plays a role in inflammatory responses through binding to the receptors CCR1, CCR4 and CCR5. Polymorphisms at this locus may be associated with both resistance and susceptibility to infection by human immunodeficiency virus type 1.[provided by RefSeq, Sep 2010]
Protein Families	Druggable Genome, Secreted Protein
Protein Pathways	Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Toll-like receptor signaling pathway

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