ZADH2 (NM_175907) Human Mass Spec Standard

Specifications

Product Data
Description	ZADH2 MS Standard C13 and N15-labeled recombinant protein (NP_787103)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC209971
Predicted MW	40.1 kDa
Protein Sequence	Sequence Link (showhide) >RC209971 protein sequence Red=Cloning site Green=Tags(s) MLRLVPTGARAIVDMSYARHFLDFQGSAIPQAMQKLVVTRLSPNFREAVTLSRDCPVPLPGDGDLLVRNR FVGVNASDINYSAGRYDPSVKPPFDIGFEGIGEVVALGLSASARYTVGQAVAYMAPGSFAEYTVVPASIA TPVPSVKPEYLTLLVSGTTAYISLKELGGLSEGKKVLVTAAAGGTGQFAMQLSKKAKCHVIGTCSSDEKS AFLKSLGCDRPINYKTEPVGTVLKQEYPEGVDVVYESVGGAMFDLAVDALATKGRLIVIGFISGYQTPTG LSPVKAGTLPAKLLKKSASVQGFFLNHYLSKYQAAMSHLLEMCVSGDLVCEVDLGDLSPEGRFTGLESIF RAVNYMYMGKNTGKIVVELPHSVNSKL TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_787103
RefSeq Size	5495
RefSeq ORF	1131
Synonyms	PRG-3
Locus ID	284273
Cytogenetics	18q22.3
Summary	Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-keto-PGE1, 15-keto-PGE2, 15-keto-PGE1-alpha and 15-keto-PGE2-alpha with highest efficienty towards 15-keto-PGE2-alpha. Overexpression represses transcriptional activity of PPARG and inhibits adipocyte differentiation.[UniProtKB/Swiss-Prot Function]
Protein Families	Druggable Genome

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