INSL3 (NM_005543) Human Mass Spec Standard

Specifications

Product Data
Description	INSL3 MS Standard C13 and N15-labeled recombinant protein (NP_005534)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC209944
Predicted MW	14.5 kDa
Protein Sequence	Sequence Link (showhide) >RC209944 protein sequence Red=Cloning site Green=Tags(s) MDPRLPAWALVLLGPALVFALGPAPTPEMREKLCGHHFVRALVRVCGGPRWSTEARRPAAGGDRELLQWL ERRHLLHGLVADSNLTLGPGLQPLPQTSHHHRHHRAAATNPARYCCLSGCTQQDLLTLCPY TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_005534
RefSeq Size	833
RefSeq ORF	393
Synonyms	ley-I-L; RLF; RLNL
Locus ID	3640
Cytogenetics	19p13.11
Summary	This gene encodes a member of the insulin-like hormone superfamily. The encoded protein is mainly produced in gonadal tissues. Studies of the mouse counterpart suggest that this gene may be involved in the development of urogenital tract and female fertility. This protein may also act as a hormone to regulate growth and differentiation of gubernaculum, and thus mediating intra-abdominal testicular descent. Mutations in this gene may lead to cryptorchidism. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2012]
Protein Families	Druggable Genome, Secreted Protein

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