IGFBP7 (NM_001553) Human Mass Spec Standard

Specifications

Product Data
Description	IGFBP7 MS Standard C13 and N15-labeled recombinant protein (NP_001544)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC209844
Predicted MW	29.1 kDa
Protein Sequence	Sequence Link (showhide) >Peptide sequence encoded by RC209844 Blue=ORF Red=Cloning site Green=Tag(s) MERPSLRALLLGAAGLLLLLLPLSSSSSSDTCGPCEPASCPPLPPLGCLLGETRDACGCCPMCARGEGE PCGGGGAGRGYCAPGMECVKSRKRRKGKAGAAAGGPGVSGVCVCKSRYPVCGSDGTTYPSGCQLRAASQ RAESRGEKAITQVSKGTCEQGPSIVTPPKDIWNVTGAQVYLSCEVIGIPTPVLIWNKVKRGHYGVQRTE LLPGDRDNLAIQTRGGPEKHEVTGWVLVSPLSKEDAGEYECHASNSQGQASASAKITVVDALHEIPVKK GEGAEL TRPLEQKLISEEDLAANDILDYKDDDDKV Recombinant protein using RC209844 also available, TP309844
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_001544
RefSeq Size	1124
RefSeq ORF	846
Synonyms	AGM; FSTL2; IBP-7; IGFBP-7; IGFBP-7v; IGFBPRP1; MAC25; PSF; RAMSVPS; TAF
Locus ID	3490
Cytogenetics	4q12
Summary	This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity, and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and one variant has been associated with retinal arterial macroaneurysm (PMID:21835307). [provided by RefSeq, Dec 2011]
Protein Families	Secreted Protein

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