TTDA (GTF2H5) (NM_207118) Human Mass Spec Standard

Specifications

Product Data
Description	GTF2H5 MS Standard C13 and N15-labeled recombinant protein (NP_997001)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC209579
Predicted MW	8.1 kDa
Protein Sequence	Sequence Link (showhide) >RC209579 protein sequence Red=Cloning site Green=Tags(s) MVNVLKGVLIECDPAMKQFLLYLDESNALGKKFIIQDIDDTHVFVIAELVNVLQERVGELMDQNAFSLTQ K TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_997001
RefSeq Size	7503
RefSeq ORF	213
Synonyms	bA120J8.2; C6orf175; TFB5; TFIIH; TGF2H5; TTD; TTD-A; TTD3; TTDA
Locus ID	404672
Cytogenetics	6q25.3
Summary	This gene encodes a subunit of transcription/repair factor TFIIH, which functions in gene transcription and DNA repair. This protein stimulates ERCC3/XPB ATPase activity to trigger DNA opening during DNA repair, and is implicated in regulating cellular levels of TFIIH. Mutations in this gene result in trichothiodystrophy, complementation group A. [provided by RefSeq, Mar 2009]
Protein Families	Transcription Factors
Protein Pathways	Nucleotide excision repair

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