ASCL2 (NM_005170) Human Mass Spec Standard

Specifications

Product Data
Description	ASCL2 MS Standard C13 and N15-labeled recombinant protein (NP_005161)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC209250
Predicted MW	20.2 kDa
Protein Sequence	Sequence Link (showhide) >RC209250 protein sequence Red=Cloning site Green=Tags(s) MDGGTLPRSAPPAPPVPVGCAARRRPASPELLRCSRRRRPATAETGGGAAAVARRNERERNRVKLVNLGF QALRQHVPHGGASKKLSKVETLRSAVEYIRALQRLLAEHDAVRNALAGGLRPQAVRPSAPRGPPGTTPVA ASPSRASSSPGRGGSSEPGSPRSAYSSDDSGCEGALSPAERELLDFSSWLGGY SGPTRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_005161
RefSeq Size	1864
RefSeq ORF	579
Synonyms	ASH2; bHLHa45; HASH2; MASH2
Locus ID	430
Cytogenetics	11p15.5
Summary	This gene is a member of the basic helix-loop-helix (BHLH) family of transcription factors. It activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. Involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system. [provided by RefSeq, Jul 2008]
Protein Families	Druggable Genome, Transcription Factors

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