CKAP1 (TBCB) (NM_001281) Human Mass Spec Standard

Specifications

Product Data
Description	TBCB MS Standard C13 and N15-labeled recombinant protein (NP_001272)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC208792
Predicted MW	27.3 kDa
Protein Sequence	Sequence Link (showhide) >RC208792 protein sequence Red=Cloning site Green=Tags(s) MEVTGVSAPTVTVFISSSLNTFRSEKRYSRSLTIAEFKCKLELLVGSPASCMELELYGVDDKFYSKLDQE DALLGSYPVDDGCRIHVIDHSGARLGEYEDVSRVEKYTISQEAYDQRQDTVRSFLKRSKLGRYNEEERAQ QEAEAAQRLAEEKAQASSIPVGSRCEVRAAGQSPRRGTVMYVGLTDFKPGYWIGVRYDEPLGKNDGSVNG KRYFECQAKYGAFVKPAVVTVGDFPEEDYGLDEI TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_001272
RefSeq Size	1475
RefSeq ORF	732
Synonyms	CG22; CKAP1; CKAPI
Locus ID	1155
Cytogenetics	19q13.12
Summary	Binds to alpha-tubulin folding intermediates after their interaction with cytosolic chaperonin in the pathway leading from newly synthesized tubulin to properly folded heterodimer (PubMed:9265649). Involved in regulation of tubulin heterodimer dissociation. May function as a negative regulator of axonal growth (By similarity).[UniProtKB/Swiss-Prot Function]

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