CLCA2 (NM_006536) Human Mass Spec Standard

CAT#: PH307731

CLCA2 MS Standard C13 and N15-labeled recombinant protein (NP_006527)



  View other "CLCA2" proteins (3)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (2)
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Specifications

Product Data
Description CLCA2 MS Standard C13 and N15-labeled recombinant protein (NP_006527)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC207731
Predicted MW 103.9 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_006527
RefSeq Size 4043
RefSeq ORF 2829
Synonyms CACC; CaCC-3; CACC3; CLCRG2
Locus ID 9635
Cytogenetics 1p22.3
Summary This gene encodes a member of the calcium-activated chloride channel regulator (CLCR) family of proteins. Members of this family regulate the transport of chloride across the plasma membrane. The encoded protein is autoproteolytically processed to generate N- and C- terminal fragments. Expression of this gene is upregulated by the tumor suppressor protein p53 in response to DNA damage. In breast cancer, expression of this gene is downregulated and the encoded protein may inhibit migration and invasion while promoting mesenchymal-to-epithelial transition in cancer cell lines. [provided by RefSeq, Sep 2016]
Protein Families Druggable Genome, Ion Channels: Other, Transmembrane
Protein Pathways Olfactory transduction
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