APJ Receptor (APLNR) (NM_005161) Human Mass Spec Standard

CAT#: PH307576

APLNR MS Standard C13 and N15-labeled recombinant protein (NP_005152)



  View other "APJ Receptor" proteins (3)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (2)
Transient overexpression lysate of apelin receptor (APLNR), transcript variant 1
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Specifications

Product Data
Description APLNR MS Standard C13 and N15-labeled recombinant protein (NP_005152)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC207576
Predicted MW 42.7 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_005152
RefSeq Size 3905
RefSeq ORF 1140
Synonyms AGTRL1; APJ; APJR; HG11
Locus ID 187
Cytogenetics 11q12.1
Summary This gene encodes a member of the G protein-coupled receptor gene family. The encoded protein is related to the angiotensin receptor, but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. It functions in the cardiovascular and central nervous systems, in glucose metabolism, in embryonic and tumor angiogenesis and as a human immunodeficiency virus (HIV-1) coreceptor. Two transcript variants resulting from alternative splicing have been identified. [provided by RefSeq, Jul 2009]
Protein Families Druggable Genome, GPCR, Transmembrane
Protein Pathways Neuroactive ligand-receptor interaction
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