IMPDH1 (NM_183243) Human Mass Spec Standard

CAT#: PH307118

IMPDH1 MS Standard C13 and N15-labeled recombinant protein (NP_899066)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Transient overexpression lysate of IMP (inosine monophosphate) dehydrogenase 1 (IMPDH1), transcript variant 3
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Specifications

Product Data
Description IMPDH1 MS Standard C13 and N15-labeled recombinant protein (NP_899066)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC207118
Predicted MW 60.4 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_899066
RefSeq Size 2517
RefSeq ORF 1689
Synonyms IMPD; IMPD1; IMPDH-I; LCA11; RP10; sWSS2608
Locus ID 3614
Cytogenetics 7q32.1
Summary The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
Protein Families Druggable Genome
Protein Pathways Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism
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