CD94 (KLRD1) (NM_002262) Human Mass Spec Standard

Specifications

Product Data
Description	KLRD1 MS Standard C13 and N15-labeled recombinant protein (NP_002253)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC206991
Predicted MW	20.5 kDa
Protein Sequence	Sequence Link (showhide) >RC206991 protein sequence Red=Cloning site Green=Tags(s) MAVFKTTLWRLISGTLGIICLSLMATLGILLKNSFTKLSIEPAFTPGPNIELQKDSDCCSCQEKWVGYRC NCYFISSEQKTWNESRHLCASQKSSLLQLQNTDELDFMSSSQQFYWIGLSYSEEHTAWLWENGSALSQYL FPSFETFNTKNCIAYNPNGNALDESCEDKNRYICKQQLI TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_002253
RefSeq Size	3258
RefSeq ORF	537
Synonyms	CD94
Locus ID	3824
Cytogenetics	12p13.2
Summary	Natural killer (NK) cells are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. Several genes of the C-type lectin superfamily, including members of the NKG2 family, are expressed by NK cells and may be involved in the regulation of NK cell function. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2017]
Protein Families	Transmembrane
Protein Pathways	Antigen processing and presentation, Graft-versus-host disease, Natural killer cell mediated cytotoxicity

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