PHLDA3 (NM_012396) Human Mass Spec Standard

CAT#: PH306751

PHLDA3 MS Standard C13 and N15-labeled recombinant protein (NP_036528)



  View other "PHLDA3" proteins (3)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (2)
Transient overexpression lysate of pleckstrin homology-like domain, family A, member 3 (PHLDA3)
    • 100 ug

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PHLDA3 rabbit polyclonal antibody
    • 25 ul

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Specifications

Product Data
Description PHLDA3 MS Standard C13 and N15-labeled recombinant protein (NP_036528)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC206751
Predicted MW 13.9 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_036528
RefSeq Size 1516
RefSeq ORF 381
Synonyms TIH1
Locus ID 23612
Cytogenetics 1q32.1
Summary p53/TP53-regulated repressor of Akt/AKT1 signaling. Represses AKT1 by preventing AKT1-binding to membrane lipids, thereby inhibiting AKT1 translocation to the cellular membrane and activation. Contributes to p53/TP53-dependent apoptosis by repressing AKT1 activity. Its direct transcription regulation by p53/TP53 may explain how p53/TP53 can negatively regulate AKT1. May act as a tumor suppressor.[UniProtKB/Swiss-Prot Function]
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