ECRG4 (NM_032411) Human Mass Spec Standard

Specifications

Product Data
Description	C2orf40 MS Standard C13 and N15-labeled recombinant protein (NP_115787)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC206239
Predicted MW	17.2 kDa
Protein Sequence	Sequence Link (showhide) >RC206239 protein sequence Red=Cloning site Green=Tags(s) MAASPARPAVLALTGLALLLLLCWGPGGISGNKLKLMLQKREAPVPTKTKVAVDENKAKEFLGSLKRQKR QLWDRTRPEVQQWYQQFLYMGFDEAKFEDDITYWLNRDRNGHEYYGDYYQRHYDEDSAIGPRSPYGFRHG ASVNYDDY TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_115787
RefSeq Size	793
RefSeq ORF	444
Synonyms	C2orf40
Locus ID	84417
Cytogenetics	2q12.2
Summary	Probable hormone that may attenuate cell proliferation and induce senescence of oligodendrocyte and neural precursor cells in the central nervous system (By similarity). ECRG4-induced senescence is characterized by G1 arrest, RB1 dephosphorylation and accelerated CCND1 and CCND3 proteasomal degradation (By similarity).[UniProtKB/Swiss-Prot Function]
Protein Families	Secreted Protein, Transmembrane

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