SPR (NM_003124) Human Mass Spec Standard

Specifications

Product Data
Description	SPR MS Standard C13 and N15-labeled recombinant protein (NP_003115)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC205679
Predicted MW	28 kDa
Protein Sequence	Sequence Link (showhide) >RC205679 protein sequence Red=Cloning site Green=Tags(s) MEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPADL GAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLTSMLCLTSSVLK AFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALEEPNVRVLNYAPGPLDTDMQQLAR ETSVDPDMRKGLQELKAKGKLVDCKVSAQKLLSLLEKDEFKSGAHVDFYDK TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_003115
RefSeq Size	1466
RefSeq ORF	783
Synonyms	SDR38C1
Locus ID	6697
Cytogenetics	2p13.2
Summary	This gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1. [provided by RefSeq, Jul 2008]
Protein Families	Druggable Genome
Protein Pathways	Folate biosynthesis, Metabolic pathways

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