TMEM59 (NM_004872) Human Mass Spec Standard

Specifications

Product Data
Description	TMEM59 MS Standard C13 and N15-labeled recombinant protein (NP_004863)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC205624
Predicted MW	36.3 kDa
Protein Sequence	Sequence Link (showhide) >RC205624 protein sequence Red=Cloning site Green=Tags(s) MAAPKGSLWVRTQLGLPPLLLLTMALAGGSGTASAEAFDSVLGDTASCHRACQLTYPLHTYPKEEELYAC QRGCRLFSICQFVDDGIDLNRTKLECESACTEAYSQSDEQYACHLGCQNQLPFAELRQEQLMSLMPKMHL LFPLTLVRSFWSDMMDSAQSFITSSWTFYLQADDGKIVIFQSKPEIQYAPHLEQEPTNLRESSLSKMSSD LQMRNSQAHRNFLEDGESDGFLRCLSLNSGWILTTTLVLSVMVLLWICCATVATAVEQYVPSEKLSIYGD LEFMNEQKLNRYPASSLVVVRSKTEDHEEAGPLPTKVNLAHSEI TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_004863
RefSeq Size	1709
RefSeq ORF	972
Synonyms	C1orf8; DCF1; HSPC001; PRO195; UNQ169
Locus ID	9528
Cytogenetics	1p32.3
Summary	This gene encodes a protein shown to regulate autophagy in response to bacterial infection. This protein may also regulate the retention of amyloid precursor protein (APP) in the Golgi apparatus through its control of APP glycosylation. Overexpression of this protein has been found to promote apoptosis in a glioma cell line. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015]
Protein Families	Transmembrane

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