VILIP1 (VSNL1) (NM_003385) Human Mass Spec Standard

Specifications

Product Data
Description	VSNL1 MS Standard C13 and N15-labeled recombinant protein (NP_003376)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC205337
Predicted MW	22.1 kDa
Protein Sequence	Sequence Link (showhide) >RC205337 protein sequence Red=Cloning site Green=Tags(s) MGKQNSKLAPEVMEDLVKSTEFNEHELKQWYKGFLKDCPSGRLNLEEFQQLYVKFFPYGDASKFAQHAFR TFDKNGDGTIDFREFICALSITSRGSFEQKLNWAFNMYDLDGDGKITRVEMLEIIEAIYKMVGTVIMMKM NEDGLTPEQRVDKIFSKMDKNKDDQITLDEFKEAAKSDPSIVLLLQCDIQK TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_003376
RefSeq Size	2014
RefSeq ORF	573
Synonyms	HLP3; HPCAL3; HUVISL1; VILIP; VILIP-1
Locus ID	7447
Cytogenetics	2p24.2
Summary	This gene is a member of the visinin/recoverin subfamily of neuronal calcium sensor proteins. The encoded protein is strongly expressed in granule cells of the cerebellum where it associates with membranes in a calcium-dependent manner and modulates intracellular signaling pathways of the central nervous system by directly or indirectly regulating the activity of adenylyl cyclase. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]
Protein Families	Druggable Genome

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