GNPTG (NM_032520) Human Mass Spec Standard

Specifications

Product Data
Description	GNPTG MS Standard C13 and N15-labeled recombinant protein (NP_115909)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC205280
Predicted MW	33.8 kDa
Protein Sequence	Sequence Link (showhide) >RC205280 representing NM_032520 Red=Cloning site Green=Tags(s) MAAGLARLLLLLGLSAGGPAPAGAAKMKVVEEPNAFGVNNPFLPQASRLQAKRDPSPVSGPVHLFRLSGK CFSLVESTYKYEFCPFHNVTQHEQTFRWNAYSGILGIWHEWEIANNTFTGMWMRDGDACRSRSRQSKVEL ACGKSNRLAHVSEPSTCVYALTFETPLVCHPHALLVYPTLPEALQRQWDQVEQDLADELITPQGHEKLLR TLFEDAGYLKTPENEPTQLEGGPDSLGFETLENCRKAHKELSKEIKRLKGLLTQHGIPYTRPTETSNLEH LGHETPRAKSPEQLRGDPGLRGSL SGPTRTRRLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_115909
RefSeq Size	1228
RefSeq ORF	912
Synonyms	C16orf27; GNPTAG; LP2537; RJD9
Locus ID	84572
Cytogenetics	16p13.3
Summary	This gene encodes the gamma sunbunit of the N-acetylglucosamine-1-phosphotransferase complex. This hexameric complex, composed of alpha, beta and gamma subunits, catalyzes the first step in synthesis of a mannose 6-phosphate lysosomal recognition marker. This enzyme complex is necessary for targeting of lysosomal hydrolases to the lysosome. Mutations in the gene encoding the gamma subunit have been associated with mucolipidosis IIIC, also known as mucolipidosis III gamma.[provided by RefSeq, Feb 2010]
Protein Families	Secreted Protein

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