SH2D1B (NM_053282) Human Mass Spec Standard

Specifications

Product Data
Description	SH2D1B MS Standard C13 and N15-labeled recombinant protein (NP_444512)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC205069
Predicted MW	15.3 kDa
Protein Sequence	Sequence Link (showhide) >RC205069 protein sequence Red=Cloning site Green=Tags(s) MDLPYYHGRLTKQDCETLLLKEGVDGNFLLRDSESIPGVLCLCVSFKNIVYTYRIFREKHGYYRIQTAEG SPKQVFPSLKELISKFEKPNQGMVVHLLKPIKRTSPSLRWRGLKLELETFVNSNSDYVDVLP TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_444512
RefSeq Size	2553
RefSeq ORF	396
Synonyms	EAT2
Locus ID	117157
Cytogenetics	1q23.3
Summary	By binding phosphotyrosines through its free SRC (MIM 190090) homology-2 (SH2) domain, EAT2 regulates signal transduction through receptors expressed on the surface of antigen-presenting cells (Morra et al., 2001 [PubMed 11689425]).[supplied by OMIM, Mar 2008]
Protein Pathways	Natural killer cell mediated cytotoxicity

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